Aberrant Blood Grouping Results in a Patient with Splenomegaly and Thrombocytopenia

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[Splenomegaly and thrombocytopenia in patients with liver cirrhosis].

BACKGROUND/AIM Splenomegaly is a frequent finding in patients with liver cirrhosis and portal hypertension and may cause hypersplenism. The occurrence of thrombocytopenia in those patients can be considered as an event with multiple etiologies. Two mechanisms may act alone or synergistically with splenic sequestration. One is central which involves either myelosuppression because of hepatitis v...

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Discrepancy in ABO Blood Grouping in a Blood Donor: A Case Report

Detection of ABO blood groups through agglutination is the basis of pre-transfusion testing. However, weak agglutination reactions may be obtained with reagent antibodies and are a result of weak expression of A and B antigens on red blood cell surface which may cause a discrepancy in blood group typing. Here, we report a donor which showed discrepancy between red blood cells (forward) and seru...

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Thrombocytopenia and splenomegaly: an unusual presentation of congenital hepatic fibrosis

Congenital hepatic fibrosis (CHF) is a rare autosomal recessive disease that primarily affects the hepatobiliary and renal systems. It is characterized by hepatic fibrosis, portal hypertension, and renal cystic disease. Firm or hard hepatomegaly is present nearly in all patients, often with a prominent left lobe, and this is usually one of the presenting signs. The haematological manifestations...

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ژورنال

عنوان ژورنال: Laboratory Medicine

سال: 2004

ISSN: 0007-5027

DOI: 10.1309/1637-l2kf-t6f7-28me